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Jeremy Dasen is deciphering the molecular code that helps developing motor neurons in the spinal cord connect with the muscles they control. Understanding this code, which relies on a large family of genes that produce proteins called Hox factors, may help scientists restore motor neuron function in people whose spinal cords have been damaged by trauma or disease. Dasen, who is at the New York University School of Medicine, has found that Hox proteins are not just present in motor neurons; they are pervasive throughout the nervous system. He plans to explore whether Hox proteins in interneurons and sensory neurons, which control motor neuron firing patterns and transmit feedback about muscle action, help assemble the complete circuits that control walking and running.
Dr. Dasen is also Assistant Professor in the Department of Physiology and Neuroscience and Member of the Smilow Neuroscience Program at New York University School of Medicine.
RESEARCH ABSTRACT SUMMARY:
Jeremy Dasen uses molecular genetics to study the role of Hox genes in the development of the vertebrate nervous system.
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Photo: Thomas Semkow
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